Three-Dimensional Protein Cage Array Capable of Active Enzyme Capture and Artificial Chaperone Activity
نویسندگان
چکیده
منابع مشابه
Three-dimensional structure of phosphotriesterase: an enzyme capable of detoxifying organophosphate nerve agents.
Organophosphates, such as parathion and paraoxon, constitute the largest class of insecticides currently used in industrialized nations. In addition, many of these compounds are known to inhibit mammalian acetylcholinesterases thereby acting as nerve agents. Consequently, organophosphate-degrading enzymes are of considerable interest in light of their ability to detoxify such compounds. Here we...
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Three-dimensional cage-like microscaffolds for cell invasion studies
Cancer cell motility is one of the major events involved in metastatic process. Tumor cells that disseminate from a primary tumor can migrate into the vascular system and, being carried by the bloodstream, transmigrate across the endothelium, giving rise to a new tumor site. However, during the invasive process, tumor cells must pass through the extracellular matrix, whose structural and mechan...
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ژورنال
عنوان ژورنال: Nano Letters
سال: 2019
ISSN: 1530-6984,1530-6992
DOI: 10.1021/acs.nanolett.9b01148